Introducing DiaMaze:

Harmonious with diverse, healthy and balanced lifestyles.

DiaMaze is clinically shown to degrade histamine found in food and beverages, thereby effectively preventing food intolerance symptoms.

In addition to enabling food intolerance sufferers to eat what they want without worry, DiaMaze is harmonious with diverse, healthy and balanced lifestyles.

DiaMaze is the only botanically sourced diamine oxidase supplement and meets organic, vegetarian, vegan, gluten-free, kosher and Halal requirements.

DiaMaze is not made from porcine or other animal products or by-products; it is not processed with any significant irradiation, genetically modified ingredients or synthetic preservatives.

What is Histamine or Food Intolerance (HIT)?

Never heard of general food or histamine intolerance? You're not the first.

Histamine (a.k.a. food intolerance) is often tough to diagnose, has a complex symptom profile, and is often confused with a multitude of other conditions. Essentially, it is an often-misunderstood food sensitivity; it is not however, a food allergy.

Histamine or food intolerance is a digestive system response to the inability to digest particular ingredients in food without involving the immune system. Conversely, a food allergy is an abnormal response to food triggered by the body's immune system.

Histamine intolerance is generally caused by a defect in the body's histamine breakdown process, in one of two enzyme systems: histamine N-methyl transferase (HMT) and diamine oxidase (DAO). Deficiency in the DAO enzyme system, found in the intestinal mucosa, has been suggested as the most probable cause of histamine intolerance.

When activity of either of these enzymes is lacking, excess histamine may cause numerous symptoms resembling allergic reactions.

Common Food Intolerance Symptoms

Symptoms may vary significantly in severity and frequency.

• Itching of the skin, eyes, ears and/or nose
• Irritated, watery eyes
• Swelling, especially facial, oral and esophageal
• Heartburn, indigestion and reflux
• Abdominal cramps and spasms
• Nasal congestion
• Runny nose
• Hives
• Nausea
• Flatulence
• Diarrhea
• Constipation
• Anxiety or panic attacks
• Chest pain
• Headaches
• Fatigue
• Chills
• Irritability
• Dizziness

Histamine-Rich Foods

Many foods contain histamine and freshness is a big factor.

For many sufferers, their own gut bacteria produces excess histamine causing symptoms. Reacting to fermented foods is a tell-tale sign of histamine intolerance, but many other foods can also be culprits. Foods that are high in histamine include:

• Processed, cured, smoked and fermented meats (lunch meat, bacon, sausage, salami, pepperoni)
• Seafood (often shellfish or fin fish, either fresh or frozen, smoked or canned)
• Leftover meat (histamine levels increase due to microbial action)
• Alcohol (especially champagne, beer and white wine)
• Breads and confectionary made with yeast
• Fermented dairy products (cheeses, yogurt, buttermilk)
• Pickled foods (pickles, sauerkraut, relish, soy products)
• Tomatoes and tomato-derived products (sauces, ketchup, soups)
• Certain vegetables (spinach, eggplant, avocado, mushrooms, canned vegetables)
• Certain spices (cayenne, curry, nutmeg, cloves, cinnamon, chili powder)
• Citrus fruits (grapefruit, oranges, lemon, lime, tangerines)
• Certain fruits (strawberries, bananas, papayas, kiwi, pineapple, mango, prunes)
• Coffee, black tea
• Vinegar
• Eggs
• Chocolate
• Peanuts, cashews, walnuts
• Mustard

About Us

30+ years of experience in producing quality enzymes.

Founded in 1975, Bio-Research Products, Inc. (BRP) specializes in the development of enzymes for biomedical manufacturing and research. BRP is recognized as the worlds leading producer of wheat germ phosphoenolpyruvate carboxylase (PEPC).

BRP provides the following services:

• Protein purification, characterization and analysis
• Diagnostic reagent components
• Custom enzyme production
• Contract manufacturing of raw material enzymes for diagnostics, pharmaceutical and industrial applications

BRP is a subsidiary of IBEX Technologies Inc., a publicly-traded biotechnology company, primarily known for its ultra-high purity recombinant heparinases and chondroitinases and for lyophilization of enzymes for medical device components.